13F
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Avoro Capital Advisors LLC

13F equity value
$10.2B
Positions
30
Top 10 concentration
76.5%
Quarters / total new picks
24 / 54
13F equity value over time
$0M$5B$10B2017201820192020202120222023202420252026

"13F equity value" = market value of this filer's US-listed long equity positions only. It excludes cash, bonds, non-US and short positions, so it understates a fund's true assets under management — often by a lot.

Not significant Verdict

13F holdings are disclosed ~45 days after quarter-end, and they never reveal when within the quarter a fund actually bought. So any 13F-based summary is structurally late and blurred — this applies to every fund, including this one.

We backtested copying it anyway. Buying this fund's new positions the day each filing went public, over 24 quarters, returned +9.7% per quarter — versus +2.8% per quarter from simply owning every 13F stock. It beat that baseline in only 41.7% of quarters (excess t = 0.02, not statistically significant). Its filings tell you what it bought — not what you should buy.

Avg 2Q excess
+0.1%
t-stat
0.02
Quarterly win rate
42%
Annualized excess
+10.5%
$1 → follow vs universe
$2.98 vs $1.72
Cumulative return: $1 invested in new picks vs universe
1.00 20180331: universe 1.04120180630: universe 0.95920180930: universe 1.00320190331: universe 0.98520190630: universe 1.05920191231: universe 0.85520200331: universe 1.03020200630: universe 1.13820200930: universe 1.39620201231: universe 1.45920210331: universe 1.47220210630: universe 1.59020210930: universe 1.42720211231: universe 1.21520220331: universe 1.30420220630: universe 1.20820220930: universe 1.29820230630: universe 1.25120230930: universe 1.42020240331: universe 1.45220240630: universe 1.58420241231: universe 1.47820250930: universe 1.66220251231: universe 1.720 20180331: follow 0.76120180630: follow 0.60820180930: follow 0.71520190331: follow 0.84620190630: follow 0.95320191231: follow 1.19420200331: follow 1.04620200630: follow 1.90320200930: follow 4.74920201231: follow 3.84320210331: follow 3.15620210630: follow 2.74120210930: follow 2.05320211231: follow 1.64120220331: follow 2.02720220630: follow 1.98320220930: follow 2.10920230630: follow 1.99620230930: follow 2.67820240331: follow 2.72620240630: follow 2.53920241231: follow 1.96720250930: follow 2.95020251231: follow 2.978 0.56 2.84 5.13 20182019202020212022202320242025 Follow Universe

Quarterly compounding, invested quarters only · entry 47 days after quarter-end (when 13F data becomes public)

Listed as facts. See the verdict above before treating this as signal.

Top 20 holdings of 30 · 2026 Q1

Ticker Value Weight QoQ
UTHR $1.6B
15.4%
HOLD
ASND $1.2B
11.4%
HOLD
MDGL $952M
9.4%
HOLD
KRYS $746M
7.3%
HOLD
ARGX $730M
7.2%
HOLD
ARWR $671M
6.6%
HOLD
KYMR $623M
6.1%
HOLD
APLS $492M
4.8%
HOLD
CNTA $454M
4.5%
TRIM
CELC $385M
3.8%
ADD
XENE $336M
3.3%
ADD
GPCR $316M
3.1%
HOLD
TERN $300M
3.0%
NEW
VERA $237M
2.3%
HOLD
RVMD $228M
2.3%
ADD
CYTK $220M
2.2%
NEW
OCUL $104M
1.0%
ADD
DMRA $98M
1.0%
NEW
QURE $97M
1.0%
TRIM
TSHA $97M
1.0%
HOLD

QoQ vs previous quarter's share count · NEW = new position · ADD/TRIM = ±2% shares · HOLD = unchanged.

Listed as facts. See the verdict above before treating this as signal.

New positions in 2026 Q1

Method & Limitations

Method: a "new position" = held this quarter, absent last quarter (options excluded; stocks with <50 prior holders excluded to filter spin-off artifacts). Entry 47 days after quarter-end — the first day the public could act on the filing. Benchmark = equal-weighted universe of all 13F-held stocks. Limitations: quarterly snapshots can't see intra-quarter trades; survivorship bias — funds that shut down are absent, which flatters the sample. Statistics, not advice.