13FPulse
KR

KRYS KRYSTAL BIOTECH INC

2026Q2 · CUSIP 501147102 · Sector: Healthcare & Biotech

Piling in

Net holder growth ranks near the top of the market

Funds that own it
416
Institutions that reported holding it to the SEC
Net increase in holders
+52
Last quarter 364 → now 416
How unusual is that
Top 5%
Stronger buying than 95% of US stocks
What the filings say, in one paragraph

416 funds held KRYS at the end of 2026Q2, up 52 from the quarter before. That is stronger buying than 95.0% of US stocks — among the most piled-into names this quarter. On the business itself, revenue over the last 12 months was $440M(YoY +22.6%), the P/E is 46.3x, return on equity is 17.8%. KRYS has had 14 buying rushes in its history, and the price moved +23.2% on average over the six months after (that is the raw price move, not how much it beat the market by). It sits in the Healthcare & Biotech sector.

How many funds owned it, quarter by quarter

Bars = net change in institutional holders, positive (green) or negative (red). Line = total institutional holders.

2017Q4: holders=12 2018Q1: holders=11 2018Q2: holders=16 2018Q3: holders=22 2018Q4: holders=44 2019Q1: holders=55 2019Q2: holders=71 2019Q3: holders=84 2019Q4: holders=89 2020Q1: holders=88 2020Q2: holders=107 2020Q3: holders=97 2020Q4: holders=108 2021Q1: holders=114 2021Q2: holders=113 2021Q3: holders=112 2021Q4: holders=140 2022Q1: holders=134 2022Q2: holders=135 2022Q3: holders=147 2022Q4: holders=154 2023Q1: holders=159 2023Q2: holders=181 2023Q3: holders=186 2023Q4: holders=193 2024Q1: holders=231 2024Q2: holders=245 2024Q3: holders=282 2024Q4: holders=263 2025Q1: holders=297 2025Q2: holders=274 2025Q3: holders=283 2025Q4: holders=334 2026Q1: holders=364 2026Q2: holders=416 -52 -26 +0 +26 +52 9223437 17Q418Q419Q420Q421Q422Q423Q424Q425Q426Q2 Net change in holders (bars) Total funds holding (line)

What happened after each past buying rush 14 times in its history

Quarter of the rush How unusual then Price, next 3 months Price, next 6 months
2026Q2 Top 5%
2026Q1 Top 20%
2025Q4 Top 10% +15.0%
2025Q1 Top 5% +8.8% +57.4%
2024Q3 Top 10% +7.0% -28.7%
2024Q2 Top 20% -7.8% -8.4%
2024Q1 Top 10% +21.1% +4.0%
2023Q2 Top 10% -15.7% -7.1%

These are the raw price moves, not how much it beat the market by. Compare them against the market over the same months — in a strong bull market almost everything is up.

Show all the numbers (large funds, value held, options…) ▾
Of them, large funds
189
Change in large funds
+21
Total value they hold
$11.1B
Funds buying for the first time
97
Funds that sold out entirely
45
Price change that quarter
+26.6%
Funds holding puts (bearish)
9
Funds holding calls (bullish)
9

These are for people who want to dig. Skip them if they do not mean anything to you — the three numbers above are enough.

8,697 institutions have filed for this quarter. 13F permits late filing and a small number arrive in the weeks after the deadline, so the holder counts and changes below may tick up.

Fundamentals

PE (TTM)
46.3
EPS (TTM)
$7.97
EPS YoY
+61.7%
Revenue (TTM)
$0.4B
Revenue YoY
+22.6%
Net margin
54.8%
ROE
17.8%
Debt ratio
9.4%
FCF (TTM)
$258M
Dividend (TTM)
No dividend
Quarterly Revenue & EPS
2021-09-30: EPS -0.70 2021-12-31: EPS -0.95 2022-03-31: EPS -1.99 2022-06-30: EPS -1.10 2022-09-30: EPS -1.17 2022-12-31: EPS -1.23 2023-03-31: EPS -1.76 2023-06-30: EPS -1.25 2023-09-30: EPS 2.79 2023-12-31: EPS 0.61 2024-03-31: EPS 0.03 2024-06-30: EPS 0.53 2024-09-30: EPS 0.91 2024-12-31: EPS 1.53 2025-03-31: EPS 1.20 2025-06-30: EPS 1.29 2025-09-30: EPS 2.66 2025-12-31: EPS 1.69 2026-03-31: EPS 1.83 2026-06-30: EPS 1.79 0M 60M 119M $M -2.19 0.44 3.07 20212022202320242025202606/26 Revenue EPS

Quarterly figures, revenue up to 10 years back; EPS split-adjusted, early quarters hidden when not calibrable

P/E (TTM) over time
4Y median 42 27 167 306 2023202420252026

P/E = close around day 47 after quarter-end ÷ TTM EPS then; this is a consistent valuation date, not the company’s actual filing date; loss quarters hidden

Quarterly free cash flow
-62M7M75M 20162017201820192020202120222023202420252026
Latest quarter $73M (2026-03-31)

FCF = operating cash flow − capex, computed from SEC XBRL; banks/insurers have no standard cash-flow structure and are hidden

As of 2026-06-30 · SEC filings (XBRL)

Email me the next update

2026 Q3 holdings are due 2026-11-16. We will email you when the refreshed lists are live.