13F
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TCG Crossover Management, LLC

13F equity value
$3.5B
Positions
49
Top 10 concentration
60.9%
Quarters / total new picks
13 / 40
13F equity value over time
$0M$2B$3B202120222023202420252026

"13F equity value" = market value of this filer's US-listed long equity positions only. It excludes cash, bonds, non-US and short positions, so it understates a fund's true assets under management — often by a lot.

Not significant Verdict

13F holdings are disclosed ~45 days after quarter-end, and they never reveal when within the quarter a fund actually bought. So any 13F-based summary is structurally late and blurred — this applies to every fund, including this one.

We backtested copying it anyway. Buying this fund's new positions the day each filing went public, over 13 quarters, returned +39.4% per quarter — versus +4.1% per quarter from simply owning every 13F stock. It beat that baseline in only 69.2% of quarters (excess t = 1.96, not statistically significant). Its filings tell you what it bought — not what you should buy.

Avg 2Q excess
+47.8%
t-stat
1.96
Quarterly win rate
69%
Annualized excess
+127.5%
$1 → follow vs universe
$18.24 vs $1.66
Cumulative return: $1 invested in new picks vs universe
1.00 20220331: universe 1.07420220930: universe 1.15320221231: universe 1.07120230331: universe 1.12920230930: universe 1.28120231231: universe 1.33920240331: universe 1.36920240630: universe 1.49320240930: universe 1.48020241231: universe 1.38120250630: universe 1.42520250930: universe 1.60220251231: universe 1.657 20220331: follow 1.21820220930: follow 5.26320221231: follow 7.19420230331: follow 6.53020230930: follow 10.55620231231: follow 12.09120240331: follow 12.62420240630: follow 16.33820240930: follow 14.00620241231: follow 12.17220250630: follow 13.89420250930: follow 19.62020251231: follow 18.242 0.92 11.05 21.19 2022202320242025 Follow Universe

Quarterly compounding, invested quarters only · entry 47 days after quarter-end (when 13F data becomes public)

Listed as facts. See the verdict above before treating this as signal.

Top 20 holdings of 49 · 2026 Q1

Ticker Value Weight QoQ
ABVX $722M
20.6%
TRIM
CGON $248M
7.1%
HOLD
TNGX $220M
6.3%
TRIM
COGT $190M
5.5%
TRIM
CNTA $170M
4.9%
HOLD
DNTH $141M
4.0%
HOLD
TYRA $124M
3.6%
ADD
IMVT $111M
3.2%
ADD
BCRX $105M
3.0%
NEW
MIRM $98M
2.8%
ADD
VOR $96M
2.8%
NEW
SYRE $96M
2.7%
HOLD
AMLX $87M
2.5%
HOLD
IRON $86M
2.5%
NEW
DYN $84M
2.4%
HOLD
GLUE $76M
2.2%
HOLD
SVRA $67M
1.9%
HOLD
RVMD $56M
1.6%
ADD
KOD $55M
1.6%
HOLD
LBRX $45M
1.3%
ADD

QoQ vs previous quarter's share count · NEW = new position · ADD/TRIM = ±2% shares · HOLD = unchanged.

Listed as facts. See the verdict above before treating this as signal.

New positions in 2026 Q1

Method & Limitations

Method: a "new position" = held this quarter, absent last quarter (options excluded; stocks with <50 prior holders excluded to filter spin-off artifacts). Entry 47 days after quarter-end — the first day the public could act on the filing. Benchmark = equal-weighted universe of all 13F-held stocks. Limitations: quarterly snapshots can't see intra-quarter trades; survivorship bias — funds that shut down are absent, which flatters the sample. Statistics, not advice.