13FPulse
PT

PTGX PROTAGONIST THERAPEUTICS INC

2026Q2 · CUSIP 74366E102 · Sector: Healthcare & Biotech

Piling in

Net holder growth ranks near the top of the market

Funds that own it
338
Institutions that reported holding it to the SEC
Net increase in holders
+27
Last quarter 311 → now 338
How unusual is that
Top 20%
Stronger buying than 88% of US stocks
What the filings say, in one paragraph

338 funds held PTGX at the end of 2026Q2, up 27 from the quarter before. That is stronger buying than 87.9% of US stocks — among the most piled-into names this quarter. On the business itself, the P/E is 141.8x, return on equity is 9.8%. PTGX has had 8 buying rushes in its history, and the price moved +11.2% on average over the six months after (that is the raw price move, not how much it beat the market by). It sits in the Healthcare & Biotech sector.

How many funds owned it, quarter by quarter

Bars = net change in institutional holders, positive (green) or negative (red). Line = total institutional holders.

2016Q4: holders=38 2017Q1: holders=40 2017Q2: holders=43 2017Q3: holders=41 2017Q4: holders=66 2018Q1: holders=70 2018Q2: holders=69 2018Q3: holders=62 2018Q4: holders=65 2019Q1: holders=64 2019Q2: holders=66 2019Q3: holders=76 2019Q4: holders=82 2020Q1: holders=77 2020Q2: holders=85 2020Q3: holders=91 2020Q4: holders=126 2021Q1: holders=128 2021Q2: holders=138 2021Q3: holders=133 2021Q4: holders=147 2022Q1: holders=140 2022Q2: holders=131 2022Q3: holders=130 2022Q4: holders=138 2023Q1: holders=136 2023Q2: holders=167 2023Q3: holders=144 2023Q4: holders=156 2024Q1: holders=185 2024Q2: holders=188 2024Q3: holders=239 2024Q4: holders=241 2025Q1: holders=271 2025Q2: holders=273 2025Q3: holders=274 2025Q4: holders=315 2026Q1: holders=311 2026Q2: holders=338 -51 -25.5 +0 +25.5 +51 34195355 16Q417Q418Q419Q420Q421Q422Q423Q424Q425Q426Q2 Net change in holders (bars) Total funds holding (line)

What happened after each past buying rush 8 times in its history

Quarter of the rush How unusual then Price, next 3 months Price, next 6 months
2026Q2 Top 20%
2025Q4 Top 20% +24.9% +21.4%
2025Q1 Top 10% +9.4% +23.4%
2024Q3 Top 5% -5.7% -4.1%
2024Q1 Top 10% +9.7% +36.3%
2023Q2 Top 10% -11.9% -11.2%
2020Q4 Top 20% +0.5% +22.2%
2019Q3 Top 20% -35.4% -9.6%

These are the raw price moves, not how much it beat the market by. Compare them against the market over the same months — in a strong bull market almost everything is up.

Show all the numbers (large funds, value held, options…) ▾
Of them, large funds
171
Change in large funds
+14
Total value they hold
$9.3B
Funds buying for the first time
71
Funds that sold out entirely
44
Price change that quarter
+45.0%
Funds holding puts (bearish)
6
Funds holding calls (bullish)
7

These are for people who want to dig. Skip them if they do not mean anything to you — the three numbers above are enough.

8,697 institutions have filed for this quarter. 13F permits late filing and a small number arrive in the weeks after the deadline, so the holder counts and changes below may tick up.

Fundamentals

PE (TTM)
141.8
EPS (TTM)
$1.03
EPS YoY
+41.1%
Revenue (TTM)
Revenue YoY
Net margin
ROE
9.8%
Debt ratio
5.0%
FCF (TTM)
$131M
Dividend (TTM)
No dividend
Quarterly Revenue & EPS
2021-09-30: EPS -0.70 2021-12-31: EPS -0.78 2022-03-31: EPS -0.43 2022-06-30: EPS -0.84 2022-09-30: EPS -0.64 2022-12-31: EPS -0.69 2023-03-31: EPS -0.67 2023-06-30: EPS -0.68 2023-09-30: EPS -0.58 2023-12-31: EPS 0.54 2024-03-31: EPS 3.26 2024-06-30: EPS -0.50 2024-09-30: EPS -0.54 2024-12-31: EPS 2.01 2025-03-31: EPS -0.19 2025-06-30: EPS -0.55 2025-09-30: EPS -0.62 2025-12-31: EPS -0.69 2026-03-31: EPS 0.05 2026-06-30: EPS 2.29 -0.92 1.33 3.59 20212022202320242025202606/26 EPS

Quarterly figures, revenue up to 10 years back; EPS split-adjusted, early quarters hidden when not calibrable

P/E (TTM) over time
4Y median 57 8 83 158 202420252026

P/E = close around day 47 after quarter-end ÷ TTM EPS then; this is a consistent valuation date, not the company’s actual filing date; loss quarters hidden

Quarterly free cash flow
-49M110M269M 20162017201820192020202120222023202420252026
Latest quarter $-49M (2026-03-31)

FCF = operating cash flow − capex, computed from SEC XBRL; banks/insurers have no standard cash-flow structure and are hidden

As of 2026-06-30 · SEC filings (XBRL)

Email me the next update

2026 Q3 holdings are due 2026-11-16. We will email you when the refreshed lists are live.