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PTGX PROTAGONIST THERAPEUTICS INC

2026Q1 · CUSIP 74366E102 · Sector: Healthcare & Biotech

Fading · Price holds, watch
Holders
310
Δ holders QoQ
-4
Breadth percentile
Top 76%
Whale holders
158
Δ whales
+1
Inst. holding value
$7.6B
New positions
52
Closed positions
56
Price momentum (1Q)
+22.2%
Put / Call
6/8

Breadth history (34 quarters)

2018Q1: Δ+4 · h=70 2018Q2: Δ-1 · h=69 2018Q3: Δ-6 · h=63 2018Q4: Δ+3 · h=66 2019Q1: Δ-1 · h=65 2019Q2: Δ+2 · h=67 2019Q3: Δ+10 · h=77 2019Q4: Δ+6 · h=83 2020Q1: Δ-5 · h=78 2020Q2: Δ+9 · h=87 2020Q3: Δ+5 · h=92 2020Q4: Δ+35 · h=127 2021Q1: Δ+2 · h=129 2021Q2: Δ+10 · h=139 2021Q3: Δ-5 · h=134 2021Q4: Δ+14 · h=148 2022Q1: Δ-7 · h=141 2022Q2: Δ-9 · h=132 2022Q3: Δ+0 · h=132 2022Q4: Δ+7 · h=139 2023Q1: Δ-2 · h=137 2023Q2: Δ+31 · h=168 2023Q3: Δ-23 · h=145 2023Q4: Δ+12 · h=157 2024Q1: Δ+29 · h=186 2024Q2: Δ+3 · h=189 2024Q3: Δ+51 · h=240 2024Q4: Δ+3 · h=243 2025Q1: Δ+30 · h=273 2025Q2: Δ+2 · h=275 2025Q3: Δ+0 · h=275 2025Q4: Δ+39 · h=314 2026Q1: Δ-4 · h=310 2018Q1: holders=70 2018Q2: holders=69 2018Q3: holders=63 2018Q4: holders=66 2019Q1: holders=65 2019Q2: holders=67 2019Q3: holders=77 2019Q4: holders=83 2020Q1: holders=78 2020Q2: holders=87 2020Q3: holders=92 2020Q4: holders=127 2021Q1: holders=129 2021Q2: holders=139 2021Q3: holders=134 2021Q4: holders=148 2022Q1: holders=141 2022Q2: holders=132 2022Q3: holders=132 2022Q4: holders=139 2023Q1: holders=137 2023Q2: holders=168 2023Q3: holders=145 2023Q4: holders=157 2024Q1: holders=186 2024Q2: holders=189 2024Q3: holders=240 2024Q4: holders=243 2025Q1: holders=273 2025Q2: holders=275 2025Q3: holders=275 2025Q4: holders=314 2026Q1: holders=310 -51 -25.5 +0 +25.5 +51 56193330 18Q119Q120Q121Q122Q123Q124Q125Q126Q1 Δ holders (bar) Holders (line)

Past Lit Events & Aftermath 7 lit events

Period Percentile Next-1Q return Next-2Q return
2025Q4 Top 14% +22.2% —
2025Q1 Top 6% +23.4% +86.0%
2024Q3 Top 4% -4.1% +13.7%
2024Q1 Top 9% +36.3% +33.7%
2023Q2 Top 6% -11.2% +52.3%
2020Q4 Top 17% +11.3% +77.1%
2019Q3 Top 19% -9.6% +50.8%

Options Sentiment

Put holders
6
QoQ: +1
Call holders
8
QoQ: -5

See methodology →

Fundamentals

PE (TTM)
—
EPS (TTM)
$-1.81
EPS YoY
-332.1%
Revenue (TTM)
$0.1B
Revenue YoY
-64.4%
Quarterly Revenue & EPS (4Y)
2022-06-30: $1M 2022-09-30: $0M 2022-12-31: $0M 2023-03-31: $0M 2023-06-30: $0M 2023-09-30: $0M 2023-12-31: $60M 2024-03-31: $255M 2024-06-30: $4M 2024-09-30: $5M 2024-12-31: $171M 2025-03-31: $28M 2025-06-30: $6M 2025-09-30: $5M 2025-12-31: $7M 2026-03-31: $56M 2022-06-30: EPS -0.84 2022-09-30: EPS -0.64 2022-12-31: EPS -0.69 2023-03-31: EPS -0.67 2023-06-30: EPS -0.68 2023-09-30: EPS -0.58 2023-12-31: EPS 0.54 2024-03-31: EPS 3.26 2024-06-30: EPS -0.50 2024-09-30: EPS -0.54 2024-12-31: EPS 2.01 2025-03-31: EPS -0.19 2025-06-30: EPS -0.55 2025-09-30: EPS -0.62 2025-12-31: EPS -0.69 2026-03-31: EPS 0.05 0M 127M 255M $M -0.92 1.33 3.59 20222023202420252026 Revenue EPS

Quarterly figures; EPS split-adjusted, early quarters hidden when not calibrable

P/E (TTM) over time
4Y median 15 2024-03-31: PE 12.12024-06-30: PE 15.22024-09-30: PE 14.92024-12-31: PE 9.12025-03-31: PE 572025-06-30: PE 76.82025-09-30: PE 130.2 8 72 137 20222023202420252026

P/E = close 47 days after quarter-end (filing date) ÷ TTM EPS then; loss quarters hidden

As of 2026-03-31 · SEC filings (XBRL)