Sofinnova Investments, Inc.
"13F equity value" = market value of this filer's US-listed long equity positions only. It excludes cash, bonds, non-US and short positions, so it understates a fund's true assets under management — often by a lot.
13F holdings are disclosed ~45 days after quarter-end, and they never reveal when within the quarter a fund actually bought. So any 13F-based summary is structurally late and blurred — this applies to every fund, including this one.
We backtested copying it anyway. Buying this fund's new positions the day each filing went public, over 31 quarters, returned +4.1% per quarter — versus +2.7% per quarter from simply owning every 13F stock. It beat that baseline in only 48.4% of quarters (excess t = 0.36, not statistically significant). Its filings tell you what it bought — not what you should buy.
Quarterly compounding, invested quarters only · entry 47 days after quarter-end (when 13F data becomes public)
Top 20 holdings of 61 · 2026 Q1
| Ticker | Value | Weight | QoQ |
|---|---|---|---|
| NTRA | $310M | | HOLD |
| BMY | $121M | | ADD |
| JAZZ | $113M | | TRIM |
| VERA | $112M | | HOLD |
| UTHR | $95M | | HOLD |
| AZN | $90M | | NEW |
| COGT | $81M | | ADD |
| RARE | $66M | | ADD |
| RAPP | $60M | | HOLD |
| INSM | $57M | | ADD |
| ALC | $55M | | ADD |
| SUPN | $49M | | ADD |
| BMRN | $44M | | ADD |
| BIIB | $42M | | NEW |
| CELC | $42M | | ADD |
| BIOA | $40M | | HOLD |
| RYTM | $39M | | ADD |
| AVBP | $39M | | HOLD |
| IDYA | $38M | | ADD |
| IMNM | $37M | | ADD |
QoQ vs previous quarter's share count · NEW = new position · ADD/TRIM = ±2% shares · HOLD = unchanged.
New positions in 2026 Q1
Method & Limitations
Method: a "new position" = held this quarter, absent last quarter (options excluded; stocks with <50 prior holders excluded to filter spin-off artifacts). Entry 47 days after quarter-end — the first day the public could act on the filing. Benchmark = equal-weighted universe of all 13F-held stocks. Limitations: quarterly snapshots can't see intra-quarter trades; survivorship bias — funds that shut down are absent, which flatters the sample. Statistics, not advice.