13F
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Darwin Global Management, Ltd.

13F equity value
$3.8B
Positions
6
Top 10 concentration
100.0%
Quarters / total new picks
15 / 36
13F equity value over time
$0M$2B$5B2020202120222023202420252026

"13F equity value" = market value of this filer's US-listed long equity positions only. It excludes cash, bonds, non-US and short positions, so it understates a fund's true assets under management — often by a lot.

Negative Verdict

13F holdings are disclosed ~45 days after quarter-end, and they never reveal when within the quarter a fund actually bought. So any 13F-based summary is structurally late and blurred — this applies to every fund, including this one.

We backtested copying it. Buying this fund's new positions the day each filing went public, over 15 quarters, returned -11.9% per quarter versus +1.9% from simply owning every 13F stock — it beat that baseline in only 20.0% of quarters (excess t = -2.14). Copying it would have systematically underperformed the simplest possible strategy.

Avg 2Q excess
-15.2%
t-stat
-2.14
Quarterly win rate
20%
Annualized excess
-55.5%
$1 → follow vs universe
$0.08 vs $1.26
Cumulative return: $1 invested in new picks vs universe
1.00 20210331: universe 1.00920210630: universe 1.09020210930: universe 0.97820211231: universe 0.83220221231: universe 0.77320230331: universe 0.81420230930: universe 0.92520231231: universe 0.96620240331: universe 0.98820240630: universe 1.07720240930: universe 1.06820241231: universe 0.99720250331: universe 1.08720250930: universe 1.22220251231: universe 1.264 20210331: follow 0.81520210630: follow 0.77720210930: follow 0.57420211231: follow 0.47520221231: follow 0.47020230331: follow 0.15420230930: follow 0.17220231231: follow 0.15220240331: follow 0.13320240630: follow 0.10120240930: follow 0.11820241231: follow 0.06720250331: follow 0.06520250930: follow 0.06620251231: follow 0.080 0.06 0.71 1.37 20212022202320242025 Follow Universe

Quarterly compounding, invested quarters only · entry 47 days after quarter-end (when 13F data becomes public)

Listed as facts. See the verdict above before treating this as signal.

Top 6 holdings of 6 · 2026 Q1

Ticker Value Weight QoQ
INSM $2.6B
68.3%
TRIM
BLTE $456M
12.1%
HOLD
ABVX $352M
9.3%
ADD
RVMD $205M
5.4%
NEW
ROIV $180M
4.8%
NEW
DNTH $1M
0.0%
NEW

QoQ vs previous quarter's share count · NEW = new position · ADD/TRIM = ±2% shares · HOLD = unchanged.

Listed as facts. See the verdict above before treating this as signal.

New positions in 2026 Q1

Method & Limitations

Method: a "new position" = held this quarter, absent last quarter (options excluded; stocks with <50 prior holders excluded to filter spin-off artifacts). Entry 47 days after quarter-end — the first day the public could act on the filing. Benchmark = equal-weighted universe of all 13F-held stocks. Limitations: quarterly snapshots can't see intra-quarter trades; survivorship bias — funds that shut down are absent, which flatters the sample. Statistics, not advice.