Casdin Capital, LLC
"13F equity value" = market value of this filer's US-listed long equity positions only. It excludes cash, bonds, non-US and short positions, so it understates a fund's true assets under management — often by a lot.
13F holdings are disclosed ~45 days after quarter-end, and they never reveal when within the quarter a fund actually bought. So any 13F-based summary is structurally late and blurred — this applies to every fund, including this one.
We backtested copying it anyway. Buying this fund's new positions the day each filing went public, over 26 quarters, returned +8.7% per quarter — versus +2.9% per quarter from simply owning every 13F stock. It beat that baseline in only 42.3% of quarters (excess t = 0.09, not statistically significant). Its filings tell you what it bought — not what you should buy.
Quarterly compounding, invested quarters only · entry 47 days after quarter-end (when 13F data becomes public)
Top 20 holdings of 40 · 2026 Q1
| Ticker | Value | Weight | QoQ |
|---|---|---|---|
| RVMD | $251M | | HOLD |
| WGS | $193M | | HOLD |
| RLAY | $143M | | ADD |
| BLFS | $114M | | HOLD |
| LAB | $82M | | HOLD |
| ILMN | $65M | | TRIM |
| GPCR | $57M | | HOLD |
| TXG | $48M | | ADD |
| DNLI | $35M | | HOLD |
| BEAM | $32M | | TRIM |
| GH | $29M | | TRIM |
| NGNE | $29M | | ADD |
| ALNY | $25M | | HOLD |
| MAZE | $23M | | HOLD |
| SRRK | $17M | | ADD |
| AGMB | $16M | | NEW |
| HIMS | $15M | | ADD |
| TSHA | $15M | | ADD |
| QGEN | $14M | | NEW |
| TEM | $13M | | HOLD |
QoQ vs previous quarter's share count · NEW = new position · ADD/TRIM = ±2% shares · HOLD = unchanged.
New positions in 2026 Q1
Method & Limitations
Method: a "new position" = held this quarter, absent last quarter (options excluded; stocks with <50 prior holders excluded to filter spin-off artifacts). Entry 47 days after quarter-end — the first day the public could act on the filing. Benchmark = equal-weighted universe of all 13F-held stocks. Limitations: quarterly snapshots can't see intra-quarter trades; survivorship bias — funds that shut down are absent, which flatters the sample. Statistics, not advice.